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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LENG8 All Species: 27.58
Human Site: S377 Identified Species: 55.15
UniProt: Q96PV6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96PV6 NP_443157.1 779 86129 S377 F M K D N S S S S S T D S R S
Chimpanzee Pan troglodytes XP_001174961 779 86160 S377 F M K D N S S S S S T D S R S
Rhesus Macaque Macaca mulatta XP_001084592 751 82765 A387 S Q R G T P G A G G A G R A R
Dog Lupus familis XP_533588 866 95014 S409 F M K D N S S S S S T D S R S
Cat Felis silvestris
Mouse Mus musculus Q8CBY3 785 86748 S415 F M K D N S S S S S T D S R S
Rat Rattus norvegicus NP_001032879 846 93215 S415 F M K D N S S S S S T D S R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521626 835 91481 S427 F M K E N S S S S S S D S R S
Chicken Gallus gallus
Frog Xenopus laevis Q32NW2 800 90307 S412 F M K E S S S S S S A G S R S
Zebra Danio Brachydanio rerio A4QNR8 839 92784 R459 S R H R D R S R H H R S D S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609459 874 99101 N447 S R S P S S S N S L K Y S S K
Honey Bee Apis mellifera XP_001121422 801 90250 R426 S R S R S K S R S R S R S R S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190105 1466 163799 S1110 R Y P A R V A S P A K G R H G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 85.4 80.1 N.A. 86.3 81.3 N.A. 71.2 N.A. 59.2 48.7 N.A. 28.7 33.5 N.A. 24.4
Protein Similarity: 100 99.4 87.2 83.7 N.A. 89.5 84.5 N.A. 77.7 N.A. 70.3 58.8 N.A. 44.1 46.8 N.A. 33
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 86.6 N.A. 73.3 6.6 N.A. 26.6 33.3 N.A. 6.6
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 100 N.A. 86.6 13.3 N.A. 40 46.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 9 9 0 9 17 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 42 9 0 0 0 0 0 0 50 9 0 0 % D
% Glu: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 9 0 9 9 0 25 0 0 17 % G
% His: 0 0 9 0 0 0 0 0 9 9 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 59 0 0 9 0 0 0 0 17 0 0 0 9 % K
% Leu: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % L
% Met: 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 50 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 9 0 9 0 0 9 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 25 9 17 9 9 0 17 0 9 9 9 17 67 9 % R
% Ser: 34 0 17 0 25 67 84 67 75 59 17 9 75 17 67 % S
% Thr: 0 0 0 0 9 0 0 0 0 0 42 0 0 0 0 % T
% Val: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _